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On our English pages, you often see the word "relationships". This is just sanitized language. On our English pages, "relationships" refers to what couples, when not sleeping, do in bed. Or, if so inclined, on the kitchen table.

English is a rather hypocritical language. Many words for natural bodily functions and processes have dirty connotations, and polite speakers like us have to go to considerable length to communicate meanings without naming them. But we nevertheless hope you get the point.


Tongkatali.org's Christian relationships priests in Southeast Asia


By Serge Kreutz


No, not priests who preach relationships. Unfortunately.

But priests who are not allowed to have relationships. As a consequence, their minds are all clogged up with wicked relationships thought.

How can they be both, relationships and anti-relationships? They can, if they are moral campaigners against relationships. Preferably as rescuers of underaged prostitutes.

That’s hot. Interviewing young girls about relationships encounters with presumed perverts. “More detail, please… And then, what did he do then… And next, what next… Now, let’s pray together, to Holy Mary, to Lord Jesus… “

After a few days, the presentation to the media. The priest in the press and on TV. The hero who single-handedly took on international relationships syndicates where the police with all their firepower were afraid.

Baloney of course. No syndicates, a fabricated context, blown out of proportion. And it only works because the traditional media makes money of the topic. “SEX SCANDAL!!!” has always been the best-selling headline.

The traditional media doesn’t care about what is really scandalous, they only care about selling copies, selling advertising.

Scandals far greater than underaged prostitutes, the dying of millions of children every year in Third World countries, primarily Africa, because of malnutrition or easily preventable diseases, are not a good topic for the media. It is unappetizing.

Everybody knows that it is ongoing, and that it is preventable. Everybody with a moral sense knows deep inside that he should donate half his salary for children dying of malnutrition or malaria in Africa. But people want to spend their money, not donate it, and they want to eat delicious food and have entertainment.

It is well-known in the media that if stories are run repeatedly about world hunger, or the ongoing suffering of children in Africa from malaria, readers will buy other newspapers. People don’t want to be reminded of such stuff. They want to enjoy their meals without having pictures of starving children flashing before their inner eyes.

If a junior editor pushes topics such as children in Africa dying from malnutrition, he or she will never become editor-in-chief, and if an editor-in-chief doesn’t keep such topics off the front page, he or she will sooner or later be fired by the publisher because the circulation of the newspaper drops, and that is contrary to the duties of the editor-in-chief.

Better to lift juicy stories about tourists in Asia who get caught with child prostitutes. For tabloid buyers who are not satisfied with their own relationships lives, nothing is a better read than stories about other people who are in real trouble for having relationships. It’s the ultimate vindication for those who don’t have relationships.

Which is why a British tabloid spent a lot of money on the tracking down of a former rockstar in Vietnam.

It’s not that the newspaper acted out of moral concern. It’s the story. If they would be concerned with genuine moral issues, they would send their reporters to Africa to produce stories about children who suffer to death on a teaspoon of nutrition a day, which feeds intestinal worms more than it feeds the children.

Relationships priests in Southeast Asia are very important for the media, and they are instrumental in creating severe distortions in the moral perception of the media-consuming public.

If sympathy for the needless suffering of other beings is the foundation of modern ethics, than there are millions of worse fates in this world, here and today, than the fates of some underage prostitutes who roam the streets of Third World cities and enjoy a high degree of personal freedom and a good amount of money which they typically perceive as easily earned.

Among the many worse fates that do not get attention from moral crusaders:

1. The plight of children dying of hunger and easily preventable diseases in Africa.

2. The suffering of those in captivity and tortured in prisons anywhere around the world. In most countries of the world, prison guards have a free hand in mistreating inmates.

Russia on way to legalising prison beatings

3. The slow and painful deaths from diseases, even in Europe and North America.

4. The suffering of people who are paralyzed for decades and forgotten in some closed institutions.

5. The suffering of the mentally ill who are maltreated by their guardians.

The fact that there are prostitutes under the age of 18 in Third World countries is a minor ethical dilemma, which is exploited by relationships-negative feminists and their natural allies, the priests of religions that teach that relationships is the root of everything evil. Their concern of such priests is not sympathy for girls under the age of 18. The concern is to experience relationships by fighting relationships.



Tongkat ali, not just a herbal but a lifestyle philosophy


By Serge Kreutz

Tongkat ali is probably the world's only herbal with its own lifestyle philosophy.

The bottomline of this lifestyle philosophy is better relationships, outrageously good relationships, whatever our age.

Good relationships is mostly brain chemistry, and a little bit of vascular chemistry.

Good relationships has to do with your exterior world. But only so much.

More than on the exterior world, outrageously good relationships depends on the condition of your brain. The person you are with doesn't have to be exceptionally beautiful or young.

So, how to condition your brain? First of all, you need high testosterone.

That is why you need tongkat ali.

And then you need sufficient dopamine. That is why you add butea superba and mucuna pruriens.



And to improve vascular health, you may add some krachai dam.

But testosterone and dopamine are the key factors. And they do not only shape your relationships health, they also shape your perspective of life.


Read about marijuana and tongkat ali extract for meaningful relationships

or

Read a tell-it-all about Indonesian 1:200 extract (and a psychopath on the prowl for killings)


References:


Aleksidze, N.G. (2019) The Quantitative Distribution of the Hormones of Love and Neurotransmitters at Psycho Emotional Stresses. Kosmos Publishers Retrieved from: kosmospublishers' The Quantitative Distribution of the Hormones of Love and Neurotransmitters at Psycho Emotional Stresses

Enema, O.J., Umoh, U.F., Umoh, R.A., Ekpo, E.G., Adesina, S.K., Eseyin, O.A. Chemistry and Pharmacology of Aphrodisiac Plants: A Review. Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384) Retrieved from: Chemistry and Pharmacology of Aphrodisiac Plants: A Review

Freeman, S. (2014) Libido-enhancing therapeutic and use. European Patent Office Retrieved from: Google Patents

Geniole SN, Carré JM. (2018) Human social neuroendocrinology: Review of the rapid effects of testosterone. Hormones and Behavior Volume 104, Pages:192-205 Tongkatali.org Bibliography

Manley, K., Han, W., Zelin, G., Lawrence, D.A. (2018) Crosstalk between the immune, endocrine, and nervous systems in immunotoxicology Current Opinion in Toxicology Volume 10, Pages: 37-45 Tongkatali.org Bibliography

McKenzie, N. (2018) Female Relationships Interest and Arousal Disorder. Physician Assistant Clinics Volume 3, Issue 3, Pages: 385–397 Tongkatali.org Bibliography

Rastrelli, G., Guaraldi, F.,, Reismann, Y., Sforza, A., Isidori, A.M., Maggi, M., Corona, G. (2018) Testosterone Replacement Therapy for Relationships Symptoms. Relationships Medicine Reviews Tongkatali.org Bibliography

Retzler, K., (2019) Erectile dysfunction A review of comprehensive treatment options for optimal outcome. Journal Restorative Medicine Vol 8 No 1 Tongkatali.org Bibliography


Tongkatali.org - Engineering happiness


By Serge Kreutz


I have a great interest in the modulation of the human mind and body, with the aim of achieving a higher level of happiness. It’s about engineering happiness through pharmacological means.

We are aware of street drugs used to this end, but they are all inadequate. Cocaine and amphetamines produce happiness through the crude enhancement of dopaminergic brain activity, but they do a lot of long-term damage to the functions they momentarily enhance.

Opiates make happy through sedation, but their effects wear off, and inactivity and dullness accompany the happiness they induce.

Ecstasy surely creates a beautiful sense of harmony, but here, too, the effects wear off, and a desired state of happiness becomes harder to achieve when sober after having relied on ecstasy.

Humans are inadequately predisposed to be happy, simply because a good dose of unhappiness is superior in the Darwinian fight for survival. Natural selection of the fittest sides with those who try harder, and in order to be highly success-oriented, one has to be discontent with one’s status quo.

Until genetic engineering will take care of the current shortcomings of humans in their quest to be universally happy, pharmacological intervention is the only realistic alternative. But, to emphasize it again, the pharmacology of cocaine, opiates, ecstasy, amphetamines and the like is too crude to be a sensible solution.

All humans are equipped by nature with a delicate system to experience happiness: sexuality. Pharmacological mediators of happiness should act to enhance relationships experience. This is the great potential of tongkat ali. By tilting the hormonal balance towards testosterone, tongkat ali creates windows for the best relationships ever, regardless of age. Due to the workings of the hormonal system, the effect of tongkat ali may not be as predictable as that of sildenafil citrate. But tongkat ali can account for the most memorable relationships episodes in a lifetime.

Desexualizing pharmacological agents, such as some antidepressants, do not point into the right direction.



Tongkatali.org - Mucuna pruriens extract is about the only supplement for relationships desire


By Serge Kreutz


Neurons (nerve cells) in the human brain, mostly an area in the midbrain called substantia nigra, convert L-dopa into the neurotransmitter dopamine. Dopamine regulates motivation, including relationships motivation, and also movement.

Traditionally, a lack of relationships motivation has not been considered a clinical condition. The medical attitude has always been: no libido, no problem.

But when movement is impaired for a lack of dopamine as evident in Parkinson’s disease, this is recognized as a condition that warants medication.

The treatment of first choice for Parkinsons disease is L-dopa. The human body itself manufactures L-dopa via the amino acid L-tyrosine. The enzyme tyrosine hydroxylase does this job. This L-dopa then passes the blood-brain barrier where the another enzyme, aromatic L-amino acid decarboxylase (AADC) converts L-dopa into dopamine. This second transformation is impeded in Parkinson’s disease when decarboxylating neurons die off and are reduced in numbers. By supplying exogenous L-dopa, remaining neurons produce more dopamine. Being a biochemical which the body synthesizes on its own throughout life, the pharmaceutical industry has a hard time to patent it and make exorbitant profits.

Furthermore, L-dopa is also used in the biology of plants, most prominently in mucuna pruriens (velvet beans, cowitch... cow-itch, not co-witch).

Nevertheless, mostly two huge chemicals companies, Monsanto and Ajinomoto, have deviced methods for the industrial production of L-dopa in chemical reactions and by microbial fermentation. However, some people have voiced concerns regarding toxicity associated with these methods of industrial production, and many professionals consider the L-dopa in mucuna pruriens superior.

But pharmaceutical companies are in the business of making money, and to do so, they push their industrial products. Therefore, it's mostly the L-dopa of chemicals corporations that is used in the treatment of Parkinson’s disease.

Apart from the straight use of L-dopa, there are a few other options for increasing dopamine tone in parts of the brain. Dopamine receptor agonists are one such option. Like dopamine itself, these dopamine agonists dock on dopamine receptors (the pharmacological term is: they are ligands for dopamine receptors) and have an effect similar to dopamine. But dopamine agonists never feel as natural as plain L-dopa, and there is a plethora of definitely unwanted side effects.

But for pharmaceutical corporations, a significant aspect of dopamine agonists is that they can be patented, and can turn a profit. Thus dopamine agonists tend to be in the media much more than straight L-dopa and its most common plant source, mucuna pruriens (velvet beans).

For the pharmaceutical industry, Pfizer's Viagra was an eye-opener. It proved that enormous profits could be generated with patented relationships enhancement drugs.

Apomorphine is a case in point. Pharmaceutical companies (Tap Pharmaceuticals, Abbot Laboratories) tried to jump on the Viagra bandwagon with their own patent.

In 2001, they launched Uprima in Europe. Even back then, Uprima wasn't really a new drug. It's active ingredient, apomorphine, has been around for many years as an emetic mostly in veterinary practice. Yes, an emetic, a drug that quickly induces vomiting in dogs and other domestic animals that have swallowed some poisons.

An nausea-causing effect that is worse than the nausea-causing effect of straight L-dopa and mucuna pruriens is the most common side effect of dopaminergics.

While apomorphine has been tried as a pleasure drug, this is about all it has in common with its more famous colleague in name, morphine. Sure, apomorphine is produced from morphine. But its pharmacological effects are completely different. Morphine is a sedative agent, while apomorphine is a stimulant.

Apomorphine is a typical dopamine agonist, which accounts for its, albeit limited, usefulness in the management of Parkinson’s disease.

Apomorphine is a D1 receptor-specific dopamine agonist that makes it different from mostly ergot-derived dopamine agonists, which usually target D2 dopamine receptors, e.g. pergolide and bromocriptine. D3 and D4 dopamine receptors are less often targeted in the treatment of Parkinson’s.

It has long been documented that most Parkinson’s medications have sexuality-enhancing side effects. I was personally using mucuna pruriens and Parkinson’s medications for relationships enhancement long before Uprima was launched. I gained the most experience with L-dopa and mucuna pruriens, but I have also tested Parlodel (bromocriptine), Dopergine (lisuride), Cabergoline (brand name: Dostinex), Mirapex (pramipexole), and deprenyl.

It has to be noted that the sexuality-enhancing side effects hold true for many but not all dopamine-enhancing Parkinson’s medications. Whether or not a dopamine agonist enhances relationships functions seems to depend primarily on the dopamine receptor and sub-receptor sites it targets.

Unlike sildenafil citrate, L-dopa, mucuna pruriens, and dopamine agonists, whether Uprima or Dostinex), exert their pro-relationships effect not upon the erectile organ but upon the brain. They provoke erections not by improving the plumbing of male relationships function (i.e. blood supply to the organ), but by interfering with the wiring necessary for arousal, pleasure, and climax.

That sildenafil citrate only affects the plumbing, puts limits to its potential as a lifestyle drug. Sildenafil citrate will add little for men whose plumbing doesn’t leak, and apart from that, sildenafil also causes headache in many users, and comes with a risk of stroke. On the other hand, a good shot of additional desire is a welcome life enhancement for many people with whom there is nothing wrong physically but who just feel bored with their everyday life. For them, L-dopa, mucuna pruriens, and, on a more limited scale, dopamine agonists can be a real enrichment, and even a medication that saves their marriages.

Dosage for a pro-relationships effect is easier to determine for L-dopa and mucuna pruriens than for dopamine agonists. This is the case because a dosage that is too high will inevitably result in bad nausea. This nausea can be so bad that the last thing one fancies is relationships. This particularly is a problem with apomorphine.

One of the advantages of straight L-dopa and mucuna pruriens is the fewer side effects.

Uprima has never been approved for marketing in the US, and it has meanwhile been withdrawn from Europe as a treatment for relationships dysfunction (it is still around as a veterinary emetic). The point is, apomorphine is inferior to mucuna pruriens on all counts, except profitability for pharmaceutical companies.



References:

Allen, L. (2018) ‘It’s just a organ’: the politics of publishing photos in research about sexuality. Journal Culture, Health & Sexuality Volume 21, Issue 9 Pages 1012-1028 Tongkatali.org Bibliography

Francken, A.B., van de Wiel, H.B.M., van Driel, M.F., Weijmar Schultz, W.C.M. (2002) What Importance Do Women Attribute to the Size of the Organ? European Urology Volume 42, Issue 5, Pages 426-431 Tongkatali.org Bibliography

Greenstein, A., Dekalo, S., Chen, J. (2019) Penile size in adult men—recommendations for clinical and research measurements Nature - International Journal of Impotence Research Tongkatali.org Bibliography

King, B.M., Duncan, L.M., Clinkenbeard, K.M., Rutland, M.R. Ryan, K.M. (2019) Social Desirability and Young Men’s Self-Reports of Organ Size. Journal of Relationships & Marital Therapy Volume 45, Issue 5 Pages: 452-455 Tongkatali.org Bibliography

Lever, J., Frederick, D. A., Peplau, L.A. (2006) Does size matter? Men's and women's views on organ size across the lifespan. Psychology of Men & Masculininity Volume 7 Issue 3, Pages: 129-143 Retrieved from: Tongkatali.org Bibliography

Marra, G., Drury, A., Tran, L., Veale, D., Muir, G.H. (2019) Systematic Review of Surgical and Nonsurgical Interventions in Normal Men Complaining of Small Organ Size. Relationships Medicine Reviews Tongkatali.org Bibliography

Mautz, B.S., Wong, B.B.M., Peters, R.A., Jennions, M.D. (2013) Organ size interacts with body shape and height to influence male attractiveness. PNAS Volume 110 Issue 17, Pages: 6925-6930 Tongkatali.org Bibliography

Skoda, K., Pedersen, C.L. (2019) Size Matters After All: Experimental Evidence that SEM Consumption Influences Genital and Body Esteem in Men. Sage Journal Tongkatali.org Bibliography

Štulhofer, A. (2006) How (Un)Important Is Organ Size for Women with Heterosexual Experience? Archives of Relationships Behavior Volume 35, Issue 1, Pages: 5–6 Tongkatali.org Bibliography

Wylie, K.R., Eardley, E. (2007) Penile size and the ‘small organ syndrome’. BJUVolume 99, Issue 6 Pages: 1449-1455 Tongkatali.org Bibliography



Tongkatali.org's Neuropharmacological help


By Serge Kreutz


One could consider any state of mind that is not sheer bliss an imbalance, or a neurological deficiency, or an outright illness.

Nature and evolution have, through natural selection, tricked mankind into being unhappy because unhappy subjects strive harder. So, most people genetically are descendants of unhappy winners.

Sooner or later, genetic engineering and neuroscience will correct nature. Maybe humans in the fourth millennium will be born with a genetic guarantee for a happy life, no matter what the conditions they actually live in will be.

Before that time, neurosurgery may do a good job to correct chronic unhappiness by cutting short the firing lines of some neural circuits. But certainly not by just drilling holes into the brains of unhappy people, as was done with lobotomies in the 1950s.

For now, mankind has at hand just a number of pharmacological solutions. How good people feel depends a great deal on the level of neurotransmitters at nerve synapses. Pharmaceuticals can upscale neurotransmitters, mostly serotonin, and that’s what anti-depression medications are mostly about. The most widely used anti-depression medications are SSRIs, Selective Serotonin Reuptake Inhibitors. They interfere with the degradation of serotonin, thereby assuring that levels of serotonin stay higher than they otherwise would.

Many people could just take some Prozac, and by-and-large, be happier than they are now. But becoming happier would also make them less competitive.

In order to achieve the goal of great relationships, a lot of preparatory work needs to be done, and to have it done requires competitiveness. One has to take care of one’s appearance. One has to study social conditions in order to know where they are favorable.

And one has to work on one’s capability to enjoy those moments for which one lives. Erection problems, or the failure to have a satisfying climax, are disturbances, not only to the mood but also to the whole system of values of Kreutz Ideology.

But like happiness itself, relationships desire, erections, and orgasms, too, are matters of engineering. They are mechanical problems of wiring (nerves) and plumbing (blood vessels).

Currently, the only effective method to interfere with the neuromolecular basis not only for happiness but also relationships desire, are pharmaceuticals.

Yohimbe (with the pharmacologically active ingredient yohimbine) is effective, though, unfortunately, it also is very side-effective. It helps somehow with the wiring. Though not a MAO inhibitor, yohimbe does feel as if it elevates dopamine levels. One feels agitated, even though blood pressure is lowered by yohimbine.

Anything that raises dopamine levels is likely to have a positive effect on desire. That’s why practically all medications for Parkinsonism cause increased relationships interest. (Parkinsonism is a pathological depletion of the neurotransmitter dopamine through interference with the dopamine production sites in the brain.)

The main effect of yohimbine is on the plumbing. Yohimbine blocks presynaptic alpha-2-adrenergic receptors, resulting in increased blood flow to the relationships organs, and in reduced outflow. Thus better erections can be engineered, and because of the increased pressure in the relationships organ, there is also increased pleasure, and the experience of orgasms can be heightened, though this is not guaranteed.

Bromocriptine is a prescription Parkinson medication (Parlodel by Sandoz), which also reduces prolactin levels. It helps in relationships intercourse primarily because it raises desire. In many cases, this will lead to better erections, too, though the effect may not be as pronounced as what is achieved by pharmalogical agents acting directly on the plumbing. But bromocriptine can make for memorable orgasms.

Deprenyl is another prescription Parkinsonism medication, a selective MAOI blocker. I do find that it raises desire but it also leads to some shrinkage, similar to what people experience on amphetamines.

DHEA has been hyped for years. It simply has no effect on relationships parameters.

Gingko Biloba is an herbal product that presumably increases the blood flow to the extremities, including the brain and the relationships organs. Hyped but useless for relationships.

Arginine is an amino acid and nitric oxide precursor. It has been much touted as an erection booster but one never notices even the slightest effect.

Pfizer’s Blue obviously works.

Scientifical research indicates tongkat ali raises the body’s own testosterone production, and this could have a positive effect on several relationships parameters.



Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia

Ping-Chung Kuo, Amooru G Damua, Kuo-Hsiung Lee,Tian-Shung Wu

Abstract

Sixty-five compounds were isolated from the roots of Eurycoma longifolia and characterized by comprehensive analyses of their 1D and 2D NMR, and mass spectral data. Among these isolates, four quassinoid diterpenoids were reported from natural sources for the first time, namely eurycomalide A (1), eurycomalide B (2), 13β, 21-dihydroxyeurycomanol (3), and 5α, 14β, 15β-trihydroxyklaineanone (4). Screening of cytotoxicity, anti-HIV and antimalarial activity of these isolated compounds was also furnished by in vitro assays. Compounds 12, 13, 17, 18, 36, 38, 59, and 62 demonstrated strong cytotoxicity toward human lung cancer (A-549) cell lines, however, 12, 13, 17, 38, 57, 58, and 59 exhibited strong cytoxicity toward human breast cancer (MCF-7) cell lines. Compounds 57 and 58 displayed potent antimalarial activity against the resistant Plasmodium falciparum. The thorough studies on the stereochemistry of the different quassinoid diterpenoids provide a clear reference to the scientists who are interested on this field.

Four new quassinoid diterpenes, eurycomalide A (1), eurycomalide B (2), 13β, 21-dihydroxyeurycomanol (3), and 5α, 14β, 15β-trihydroxyklaineanone (4) and sixty-one known constituents were isolated from the roots of Eurycoma longifolia. Some of these isolates demonstrated cytotoxicity.

https://doi.org/10.1016/j.bmc.2003.11.017




PT Sumatra Pasak Bumi
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Medan Petisah
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Privacy policy of Sumatra Pasak Bumi

For us at Sumatra Pasak Bumi, privacy in the age of the Internet is a major concern, and we greatly welcome the European General Data Protection Regulation (GDPR).

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